Lab testing equipment

Headspace Analysis (HSA) as a test method for leak testing is based on the detection of a certain trace gas in the headspace of the test object. The Bombing method patented by WILCO allows the gas concentration to change in the event of a leak in the shortest possible time – even for test samples without vacuum in the headspace. This enables the HSA Method to be used for many applications such as:

• For leaks in headspace and in product area
• Shelf for bombing of multiple containers parallel
• Inserts for dry ice to simulate deep cold storage conditions
• Pressure profiles for simulation of transport condition, storage over shelf life and as alternative to dye ingress testing

Using a combination of bombing and Headspace Analysis offers many advantages:

• Sensitivities down to one order below the MALL (0.01 µm)
• Integration with other CCIT applications (multi use)
• Can be applied to the full finished and close container
• Permeation is much slower than with He leak testing
• Non-destructive inspection method

Headspace Analysis (HSA) is a trusted method for Container Closure Integrity Testing (CCIT), especially for lyophilized products filled under vacuum where air ingress naturally occurs.

Now, this proven technology can also be applied to liquid-filled containers - thanks to a controlled headspace modification process. By exposing samples to CO₂ under overpressure, even the smallest leaks allow the tracer gas to enter, making them detectable with unmatched precision.

The key lies in the optimized bombing cycle, which defines the final sensitivity of the test and enables leak detection down to 1 µm.
This innovative approach extends the benefits of HSA to liquid products - delivering non-destructive, highly sensitive, and reliable integrity testing.

All transport scenarios can be imitated by bombing lab equipment. Therefore an optical analysis of moveable parts of the container is integrated in order to monitor the plunger position in the pre-filled syringe over pressure cycles.