Parenteral drug products are required to be 100% visually inspected. As each product and its packaging define their specific inspection task, standardized inspection setups may lead to a high level of false rejects and underperforming inspection results. In contrast, a highly customized solution provides the opportunity to take the inspection to the next level.

Inspection for particles and cosmetic defects

Inspection tasks are product and process specific and require an individual treatment in order to achieve the best possible outcome. Our Vision CAV platform is designed for a highly flexible setup allowing the integration of different optical setups.

Static optical path

As movements and vibrations may impact image quality and the inspection outcome accordingly, our philosophy is not have any moving parts or components in the optical path meaning that all lightings, optics and cameras are in a fixed position and are neither swiveling nor rotating.

Optical Setup

Our optical setups consist of the latest digital high-speed cameras and lighting components. Light setups and camera types are selected according to the individual inspection task.

For cosmetic defect, inspection samples are rotated by 360°. This allows an inspection for cracks, scratches and other defects on the container wall and closure.

For instance, in certain cosmetic defect inspections, color cameras are used to make cracks visible.

In addition to the inspection of cosmetic defects, automated particle inspection for parenteral drugs is a major task. Typical visible particle types to be inspected are metal, rubber, glass and fibers in the range of 50-70µm. For particle inspection in liquids the particles are set in motion by spinning. Image sequences are then taken and further processed for the identification of particles. For lyophilized products or highly viscous products the spinning may not be applied, and thus other optical setups are put in place.

Our Visual inspection systems provide the following benefits

  • Customized optical setup optimized for inspection tasks
  • Latest digital camera technology
  • Reduction of vibrations throughout the system
  • No moving or adjustment of optics required – simple qualification of optical setup
  • No dead angles in optical path
  • Scalable processing units for a simple upgrade and exchange
  • State-of-the-art image processing